BDBM451773 US10710980, Example 5::US10947218, Example 5

SMILES Nc1ncc(cc1C(=O)N[C@H]1CC[C@H](O)CC1)-c1ccc(cc1)[C@]12C[C@H]1CN(CCCN1CCOCC1)C2

InChI Key InChIKey=FCURQEMLQWEPFI-VWDBNSKXSA-N

Data  14 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 451773   

TargetBone morphogenetic protein receptor type-1A [198-525](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451773(US10710980, Example 5 | US10947218, Example 5)
Affinity DataIC50:  1.10E+3nMAssay Description:The assays were performed in 384-well, low volume microtiter assay plates in a final reaction volume of 6 ul. Dose-response curves were generated by ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetBone morphogenetic protein receptor type-1A [198-525](Homo sapiens (Human))
Novartis

US Patent
LigandPNGBDBM451773(US10710980, Example 5 | US10947218, Example 5)
Affinity DataIC50:  1.10E+3nMAssay Description:A kinase selectivity panel which measures autophosphorylation using the ADP-Glo Kinase Assay (Promega, V9101) was set-up for wild-type ALK2 (aa172-49...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent